Pseudo-MRM method for the selective detection of truncated tissue factor

A pseudo-MRM method using high-resolution mass spectrometry is presented for the specific detection of truncated tissue factor (tTF), retargeted to tumor vasculature by GNGRAHA peptide (tTF-NGR), in serum. In order to increase sensitivity, serum proteins are pre-separated by 1D-gel electrophoresis a...

Verfasser: König, Simone
Harrach, Saliha
Berdel, Wolfgang E.
Schwöppe, Christian
FB/Einrichtung:FB 05: Medizinische Fakultät
Dokumenttypen:Artikel
Medientypen:Text
Erscheinungsdatum:2017
Publikation in MIAMI:02.11.2017
Datum der letzten Änderung:23.03.2022
Quelle:Mercator Journal of Biomolecular Analysis, 1 (2017) 2, S. 22-32
Angaben zur Ausgabe:[Electronic ed.]
Schlagwörter:mass spectrometry; protein quantification; serum; tumor; LC/MS
Fachgebiet (DDC):572: Biochemie
Lizenz:CC BY-SA 3.0 DE
Sprache:English
Format:PDF-Dokument
URN:urn:nbn:de:hbz:6-00269468510
Permalink:https://nbn-resolving.de/urn:nbn:de:hbz:6-00269468510
Onlinezugriff:mercator-journal_2017_1_2_22-32.pdf
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