Validation of the Kidney Donor Profile Index (KDPI) to assess a deceased donor’s kidneys’ outcome in a European cohort

The Kidney Donor Profile Index (KDPI) was introduced in the United States in 2014 to guide the decision making of clinicians with respect to accepting or declining a donated kidney. To evaluate whether the KDPI can be applied to a European cohort, we retrospectively assessed 580 adult patients who u...

Authors: Dahmen, Maximilian
Becker, Felix
Pavenstädt, Hermann-Joseph
Suwelack, Barbara
Schütte-Nütgen, Katharina
Reuter, Stefan Johannes
Division/Institute:FB 05: Medizinische Fakultät
Document types:Article
Media types:Text
Publication date:2019
Date of publication on miami:03.07.2020
Modification date:03.07.2020
Edition statement:[Electronic ed.]
Source:Scientific Reports 9 (2019) 11234, 1-11
Subjects:Outcomes research; Renal replacement therapy
DDC Subject:610: Medizin und Gesundheit
License:CC BY 4.0
Language:English
Funding:Finanziert durch den Open-Access-Publikationsfonds der Westfälischen Wilhelms-Universität Münster (WWU Münster).
Format:PDF document
URN:urn:nbn:de:hbz:6-30189601271
Other Identifiers:DOI: 10.1038/s41598-019-47772-7
Permalink:https://nbn-resolving.de/urn:nbn:de:hbz:6-30189601271
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Digital documents:artikel_reuter_2019.pdf
zusatzmaterial_reuter_2019.pdf
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The Kidney Donor Profile Index (KDPI) was introduced in the United States in 2014 to guide the decision making of clinicians with respect to accepting or declining a donated kidney. To evaluate whether the KDPI can be applied to a European cohort, we retrospectively assessed 580 adult patients who underwent renal transplantation (brain-dead donors) between January 2007 and December 2014 at our center and compared their KDPIs with their short- and long-term outcomes. This led to the observation of two associations: one between the KDPI and the estimated glomerular filtration rate at one year (1-y-eGFR) and the other between the KDPI and the death-censored allograft survival rate (both p