Selenium supplementation in radiotherapy patients: do we need to measure selenium levels in serum or blood regularly prior radiotherapy?

Considering the review by Puspitasari and colleagues, an additional discussion of the endpoints of the Se supplementation studies described would be helpful. In our view, selenium can safely be given to selenium-deficient cancer patients prior to and during radiotherapy. Therefore, in order to help...

Authors: Mücke, Ralph
Micke, Oliver
Schomburg, Lutz
Kisters, Klaus
Büntzel, Jens
Hübner, Jutta
Kriz, Jan
Division/Institute:FB 05: Medizinische Fakultät
Document types:Article
Media types:Text
Publication date:2014
Date of publication on miami:22.01.2015
Modification date:21.01.2020
Edition statement:[Electronic ed.]
Source:Radiation Oncology 9 (2014) 289, 1-2
Subjects:Selenium; Supplementation; Clinical studies; Selenoproteins; Radiotherapy
DDC Subject:610: Medizin und Gesundheit
License:CC BY 4.0
Language:English
Notes:Finanziert durch den Open-Access-Publikationsfonds 2014/2015 der Deutschen Forschungsgemeinschaft (DFG) und der Westfälischen Wilhelms-Universität Münster (WWU Münster).
Format:PDF document
ISSN:1748-717X
URN:urn:nbn:de:hbz:6-60379584649
Permalink:http://nbn-resolving.de/urn:nbn:de:hbz:6-60379584649
Other Identifiers:DOI: doi:10.1186/s13014-014-0289-0
Digital documents:s13014-014-0289-0.pdf

Considering the review by Puspitasari and colleagues, an additional discussion of the endpoints of the Se supplementation studies described would be helpful. In our view, selenium can safely be given to selenium-deficient cancer patients prior to and during radiotherapy. Therefore, in order to help the radiation oncologist in decision making, we strongly advocate to determine the selenium status prior to and during a potential adjuvant selenium supplementation, e.g. when trying to ease the side-effects of radiation treatment or in the aftercare situation when the selenium status may become insufficient.