Gender differences in acute myocardial infarction—A nationwide German real-life analysis from 2014 to 2017
Background: Female sex was reported to be associated with an unfavorable outcome in acute myocardial infarction (AMI). In this nationwide analysis we assessed sex differences in acute outcomes of AMI and recent trends in patient healthcare. Methods: We analyzed 875 735 German cases hospitalized with...
| Verfasser: | |
|---|---|
| FB/Einrichtung: | FB 05: Medizinische Fakultät |
| Dokumenttypen: | Artikel |
| Medientypen: | Text |
| Erscheinungsdatum: | 2021 |
| Publikation in MIAMI: | 05.05.2023 |
| Datum der letzten Änderung: | 05.05.2023 |
| Angaben zur Ausgabe: | [Electronic ed.] |
| Quelle: | Clinical Cardiology 44 (2021) 7, 890-898 |
| Schlagwörter: | acute coronary syndrome; epidemiology; gender; health care research; multivariable logistic regression analysis; women |
| Fachgebiet (DDC): | 610: Medizin und Gesundheit |
| Lizenz: | CC BY 4.0 |
| Sprache: | English |
| Förderung: | Finanziert über die DEAL-Vereinbarung mit Wiley 2019-2022. Förderer: Wissenschaftliches Institut der AOK / Projektnummer: 01VSF18051 |
| Format: | PDF-Dokument |
| URN: | urn:nbn:de:hbz:6-50049684981 |
| Weitere Identifikatoren: | DOI: 10.17879/20059616515 |
| Permalink: | https://nbn-resolving.de/urn:nbn:de:hbz:6-50049684981 |
| Verwandte Dokumente: |
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| Onlinezugriff: | 10.1002_clc.23662.pdf |
Background: Female sex was reported to be associated with an unfavorable outcome in acute myocardial infarction (AMI). In this nationwide analysis we assessed sex differences in acute outcomes of AMI and recent trends in patient healthcare. Methods: We analyzed 875 735 German cases hospitalized with a main diagnosis of ST- (STEMI) and non ST-elevation myocardial infarction (NSTEMI) between January 01 2014 and December 31 2017 regarding morbidity, in-hospital mortality and treatments. A multivariable logistic regression model was designed to evaluate the use of interventions and their impact on in-hospital mortality. Results: STEMI cases decreased from 72 894 in 2014 to 68 213 in 2017, with 70% assignable to men. Female sex was associated with older age (74 vs. 62 years), and higher prevalence of cardiovascular risk factors such as chronic kidney disease (19.2% vs. 12.5%), hypertension (69.0% vs. 65.0%) and left ventricular heart failure (36.0% vs. 32.1%). In NSTEMI, female sex was also associated with older age (78 vs. 71 years), and higher prevalence of cardiovascular risk factors such as chronic kidney disease (29.7% vs. 23.9%), hypertension (77.4% vs. 74.5%) and left ventricular heart failure (40.5% vs. 36.4%). Overall, 74.3% of female and 81.3% of male STEMI cases received percutaneous coronary intervention (PCI, p