Baseline Characteristics and Prescription Patterns of Standard Drugs in Patients with Angiographically Determined Coronary Artery Disease and Renal Failure (CAD-REF Registry)

BACKGROUND: Chronic kidney disease (CKD) is strongly associated with coronary artery disease (CAD). We established a prospective observational nationwide multicenter registry to evaluate current treatment and outcomes in patients with both CKD and angiographically documented CAD. METHODS: In 32 card...

Authors: Reinecke, Holger
Breithardt, Günter
Engelbertz, Christiane Maria
Schmieder, Roland E.
Fobker, Manfred
Pinnschmidt, Hans O.
Schmitz, Boris
Bruland, Philipp
Wegscheider, Karl
Pavenstädt, Hermann
Brand, Eva
Division/Institute:FB 05: Medizinische Fakultät
FB 13: Biologie
Document types:Article
Media types:Text
Publication date:2016
Date of publication on miami:30.05.2016
Modification date:28.01.2021
Edition statement:[Electronic ed.]
Source:PLoS ONE 11 (2016) 2, e0148057, 1-16
DDC Subject:610: Medizin und Gesundheit
License:CC BY 4.0
Language:English
Notes:Finanziert durch den Open-Access-Publikationsfonds 2015/2016 der Westfälischen Wilhelms-Universität Münster (WWU Münster).
Format:PDF document
ISSN:1932-6203
URN:urn:nbn:de:hbz:6-15289615082
Other Identifiers:DOI: 10.1371/journal.pone.0148057
Permalink:https://nbn-resolving.de/urn:nbn:de:hbz:6-15289615082
Digital documents:journal.pone.0148057.PDF

BACKGROUND: Chronic kidney disease (CKD) is strongly associated with coronary artery disease (CAD). We established a prospective observational nationwide multicenter registry to evaluate current treatment and outcomes in patients with both CKD and angiographically documented CAD. METHODS: In 32 cardiological centers 3,352 CAD patients with ≥50% stenosis in at least one coronary artery were enrolled and classified according to their estimated glomerular filtration rate and proteinuria into one of five stages of CKD or as a control group. RESULTS: 2,723 (81.2%) consecutively enrolled patients suffered from CKD. Compared to controls, CKD patients had a higher prevalence of diabetes, hypertension, peripheral artery diseases, heart failure, and valvular heart disease (each p