Radiotherapy in the GHSG HD 16 and HD 17 trials – quality assurance and dosimetric analysis for Hodgkin lymphoma in the modern era
Introduction: Radiotherapy (RT) is an integral part of treatment concepts for early-stage Hodgkin lymphoma. The following analysis reports on RT-quality in the recent HD16 and 17 trials of the German Hodgkin Study Group (GHSG). Methods: All RT-plans of involved-node RT (INRT) in HD 17 were requested...
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FB/Einrichtung: | FB 05: Medizinische Fakultät |
Dokumenttypen: | Artikel |
Medientypen: | Text |
Erscheinungsdatum: | 2022 |
Publikation in MIAMI: | 05.01.2023 |
Datum der letzten Änderung: | 05.01.2023 |
Angaben zur Ausgabe: | [Electronic ed.] |
Quelle: | Advances in Radiation Oncology (2022), 101169 |
Fachgebiet (DDC): | 610: Medizin und Gesundheit |
Lizenz: | CC BY-NC-ND 4.0 |
Sprache: | English |
Format: | PDF-Dokument |
URN: | urn:nbn:de:hbz:6-51069416122 |
Weitere Identifikatoren: | DOI: 10.17879/51069418081 |
Permalink: | https://nbn-resolving.de/urn:nbn:de:hbz:6-51069416122 |
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Onlinezugriff: | 10.1016_j.adro.2022.101169.pdf |
Introduction: Radiotherapy (RT) is an integral part of treatment concepts for early-stage Hodgkin lymphoma. The following analysis reports on RT-quality in the recent HD16 and 17 trials of the German Hodgkin Study Group (GHSG). Methods: All RT-plans of involved-node RT (INRT) in HD 17 were requested for analysis, along with 100 and 50 involved-field RT (IFRT) plans in HD 16 and 17, respectively. A structured assessment regarding field design and protocol adherence was performed by the reference radiation oncology panel of the GHSG. Results: Overall, 100 (HD 16) and 176 (HD 17) patients were eligible for analysis. In HD 16, 84 % of RT series were evaluated as correct, with significant improvement compared to the predecessor studies (p< 0.001). In HD 17, 76.1 % of INRT-cases revealed a correct RT design compared to 69.1 % of IFRT-cases, which was superior to prior studies (p