Two-stage revision hip arthroplasty with a cementless stem in cases of periprosthetic joint infection

Background: Two-stage revision arthroplasty is today regarded as the gold standard treatment method for deep prosthetic joint infection. The aim of the present study was to evaluate clinical and functional outcomes with the Modular Universal Tumor And Revision System (MUTARS) RS stem in patients und...

Authors: Dieckmann, Ralf
Schulz, Dino Georg
Gosheger, Georg
Becker, Karsten
Daniilidis, Kiriakos
Streitbürger, Arne
Hardes, Jendrik
Höll, Steffen
Division/Institute:FB 05: Medizinische Fakultät
Document types:Article
Media types:Text
Publication date:2014
Date of publication on miami:09.01.2015
Modification date:16.04.2019
Edition statement:[Electronic ed.]
Source:BMC Musculoskeletal Disorders 15 (2014) 398, 1-7
Subjects:Two-stage revision; Periprosthetic infection; Hip arthroplasty; Cementless; Modular; Hexagonal
DDC Subject:610: Medizin und Gesundheit
License:CC BY 4.0
Language:English
Notes:Finanziert durch den Open-Access-Publikationsfonds 2014/2015 der Deutschen Forschungsgemeinschaft (DFG) und der Westfälischen Wilhelms-Universität Münster (WWU Münster).
Format:PDF document
ISSN:1471-2474
URN:urn:nbn:de:hbz:6-90389605501
Permalink:http://nbn-resolving.de/urn:nbn:de:hbz:6-90389605501
Other Identifiers:DOI: doi:10.1186/1471-2474-15-398
Digital documents:1471-2474-15-398.pdf

Background: Two-stage revision arthroplasty is today regarded as the gold standard treatment method for deep prosthetic joint infection. The aim of the present study was to evaluate clinical and functional outcomes with the Modular Universal Tumor And Revision System (MUTARS) RS stem in patients undergoing two-stage revisions. Methods: The functional and clinical outcomes for 43 patients who had undergone two-stage revision procedures for PJI were analyzed in a retrospective study. The minimum follow-up period was 24 months. Shorter follow-up periods were only observed when there were complications such as loosening or recurrent infection. The mean follow-up period was 3.86 years (range 7 months to 11.6 years). Results: The success rate with infection control for PJI was 93%. Reinfection occurred in four cases (7%). The risk of reinfection after MRSA infection was 20.5 times greater (P >0.01) than with sensitive or unknown bacteria. Two aseptic loosening occurred after 7 and 20 months. The average Harris Hip Score was 80 (range 62–93). Conclusion: This retrospective study showed a 93% rate of eradication using specific antibiotic therapy. With the modular MUTARS RS stem, there was a low rate of aseptic loosening of 4.6%. MRSA infection was identified as a risk factor for reinfection. The two-stage procedure with modular cementless implants used is therefore appropriate for treating periprosthetic infections associated with hip endoprostheses.