This paper is directed to stakeholders from the private sector, public institutions, civil society, and academia that have to do with the production and use of chemicals or climate change, be it in a direct form or indirectly in advisory institutions, research, or government and regulatory bodies. It is meant as a contribution to the discussion on the nexus between chemistry and climate change, presenting the chemical industry as a key sector for building pathways towards climate neutrality. The findings presented in this paper are based on the learning experience of an international cooperation project with developing countries and emerging economies, named Climate Action Programme for the Chemical Industry (CAPCI) (ISC3, 2023). It seeks to inform and inspire the reader on potentials of the chemical industry for implementing GHG mitigation strategies and contributing to achieve climate targets. Furthermore, it shows possibilities for the transfer of knowledge and experiences between industrialized countries and developing or emerging countries as well as south-south collaboration. As chemicals production and use are characterized by international value chains with a growing share of developing countries and emerging economies, international cooperation and knowledge sharing are crucial drivers for enhancing their successful transformation.