Target analysis for the Cys-cluster tryptic peptide of acylated transglutaminase 1

Transglutaminase 1 (TGase1) is modified by myristoylation and palmitoylation supposedly in its cysteine cluster region. In order to monitor acylation in protein expression we developed a target mass spectrometry method using synthetic peptide SFWARCPalmCamGCamCamSCamR as a standard. It is palmitoyla...

Authors: König, Simone
Bayer, Malte
Wiegmann, Henning
Division/Institute:FB 05: Medizinische Fakultät
Document types:Article
Media types:Text
Publication date:2019
Date of publication on miami:19.12.2019
Modification date:19.12.2019
Source:Mercator Journal of Biomolecular Analysis, 3 (2019) 2, S. 1-5
Edition statement:[Electronic ed.]
Subjects:Transglutaminase 1; ichthyosis; palmitoylation; myristoylation; MRM Transglutaminase 1; Ichthyose; Palmitoylierung; Myristoylierung; MRM
DDC Subject:572: Biochemie
License:CC BY-SA 3.0 DE
Format:PDF document
Digital documents:mercator_journal_2019_3_2_1-5.pdf