Phylogenetic analysis reveals wide distribution of globin X

The vertebrate globin gene repertoire consists of seven members that differ in terms of structure, function and phyletic distribution. While hemoglobin, myoglobin, cytoglobin, and neuroglobin are present in almost all gnathostomes examined so far, other globin genes, like globin X, are much more res...

Authors: Dröge, Jasmin Sybille
Makałowski, Wojciech
Division/Institute:FB 05: Medizinische Fakultät
Document types:Article
Media types:Text
Publication date:2011
Date of publication on miami:14.02.2013
Modification date:07.07.2021
Edition statement:[Electronic ed.]
Source:Biology Direct 6 (2011) 54
DDC Subject:570: Biowissenschaften; Biologie
License:CC BY 2.0
Language:English
Notes:Finanziert durch den Open-Access-Publikationsfonds 2011/2012 der Deutschen Forschungsgemeinschaft (DFG) und der Westfälischen Wilhelms-Universität Münster (WWU Münster).
Format:PDF document
URN:urn:nbn:de:hbz:6-47389400000
Other Identifiers:DOI: 10.1186/1745-6150-6-54
Permalink:https://nbn-resolving.de/urn:nbn:de:hbz:6-47389400000
Digital documents:1745-6150-6-54.pdf

The vertebrate globin gene repertoire consists of seven members that differ in terms of structure, function and phyletic distribution. While hemoglobin, myoglobin, cytoglobin, and neuroglobin are present in almost all gnathostomes examined so far, other globin genes, like globin X, are much more restricted in their phyletic distribution. Till today, globin X has only been found in teleost fish and Xenopus. Here, we report that globin X is also present in the genomes of the sea lamprey, ghost shark and reptiles. Moreover, the identification of orthologs of globin X in crustacean, insects, platyhelminthes, and hemichordates confirms its ancient origin.