A laboratory manual of kidney perfusion techniques

An organ such as the kidney naturally functions best in a healthy organism. Once a kidney has been removed from its normal context, it is crucial to find the optimal compromise between the demands of the problem at issue and the experimental model to be adopted. An isolated kidney is, in effect, a “...

Author: Schurek, Hans-Joachim
Further contributors: Neumann, Klaus Hinrich (Collaborator)
Schweda, Frank (Collaborator)
Czogalla, Jan (Collaborator)
Document types:Book
Media types:Text
Publication date:2017
Date of publication on miami:06.07.2017
Modification date:20.01.2021
Series:Wissenschaftliche Schriften der WWU Münster / Reihe V, Bd. 6
Publisher: readbox unipress in der readbox publishing GmbH
Edition statement:[Electronic ed.]
Subjects:isoliert perfundierte Niere; Sauerstoff; Modellvarianten; Konzentrierfähigkeit isolated perfused kidney; oxygen; different modalities; concentrating capacity
DDC Subject:610: Medizin und Gesundheit
License:CC BY-SA 4.0
Language:English
Notes:Auch im Buchhandel erhältlich: A Laboratory Manual of Kidney Perfusion Techniques / Hans-Joachim Schurek; In collaboration with Klaus Hinrich Neumann, Frank Schweda and Jan Czogalla. – Münster : Münsterscher Verlag für Wissenschaft, 2017. – VIII, 228 S. (Wissenschaftliche Schriften der WWU Münster : Reihe V ; Bd. 6), ISBN 978-3-8405-0154-8, Preis: 71,50 EUR
Deutsche Ausgabe 2015 unter dem Titel "Laborhandbuch Nierenperfusion" erschienen, http://nbn-resolving.de/urn:nbn:de:hbz:6-88219516586, https://doi.org/10.17879/67229530894
The book was also published on the bookshelf of the National Library Medicine: https://www.ncbi.nlm.nih.gov/books/NBK565898/.
Format:PDF document
ISBN:978-3-8405-0154-8
URN:urn:nbn:de:hbz:6-22259740573
Other Identifiers:DOI: 10.17879/61219766654
Permalink:https://nbn-resolving.de/urn:nbn:de:hbz:6-22259740573
Digital documents:schurek_buchblock_en.pdf

An organ such as the kidney naturally functions best in a healthy organism. Once a kidney has been removed from its normal context, it is crucial to find the optimal compromise between the demands of the problem at issue and the experimental model to be adopted. An isolated kidney is, in effect, a “dying kidney”, although it may continue to function for between 1 and 4 hours, depending on one's definition of normal. The basic reason for the progressive deterioration in function can be found in the stresses set up by the transition from perfusion by whole blood to the use of a more or less artificial perfusing medium. Indeed, blood is a “liquid organ”, a highly complex cocktail that is steadily being reconditioned by the actions of other organs, and this complexity explains why all efforts to maintain kidney function in isolation are ultimately doomed to failure. If we want to approach its fantastic properties, then we should leave an organ as the kidney within the body. As Mephisto remarks in Goethe's drama “Faust”, Studierzimmer II: “Blut ist ein ganz besondrer Saft”: “blood is a quite special juice”.